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Назва: Impact of the initial clinical presentation on the outcome of patients with infective endocarditis.
Автори: Motoc, Andreea.;
Kessels, Jolien.;
Roosens, Bram.;
Lacor, Patrick.;
Van de Veire, Nico.;
De Sutter, Johan.;
Magne, Julien.;
Droogmans, Steven.;
Cosyns.;, Bernard.;
Ключові слова: infective endocarditis,
clinical presentation,
cardiac surgery,
in-hospital mortality.
Дата публікації: 7-лип-2021
Видавництво: Cardiology Journal .
Бібліографічний опис: Cardiology Journal .-2023,vol.30,N3.
Короткий огляд (реферат): Background: Infective endocarditis (IE) is a life-threatening disease. Despite advancements in diagnostic methods, the initial clinical presentation of IE remains a valuable asset. Therefore, the impact of clinical presentation on outcomes and its association with microorganisms and IE localization were assessed herein. Methods: This retrospective study included 183 patients (age 68.9 ± 14.2 years old, 68.9% men) with definite IE at two tertiary care hospitals in Belgium. Demographic data, medical history, clinical presentation, blood cultures, imaging data and outcomes were recorded. Results: In-hospital mortality rate was 22.4%. Sixty (32.8%) patients developed embolism, 42 (23%) shock, and 103 (56.3%) underwent surgery during hospitalization. Shock at admission predicted embolism during hospitalization (odds ratio [OR] 2.631, 95% confidence interval [CI] 1.119–6.184, p = 0.027). A new cardiac murmur at admission predicted cardiac surgery (OR 1.949, 95% CI 1.007– –3.774, p = 0.048). Methicillin resistant Staphylococcus aureus predicted in-hospital mortality and shock (p = 0.005, OR 6.945, 95% CI 1.774–27.192 and p = 0.015, OR 4.691, 95% CI 1.348–16.322, respectively). Mitral valve and aortic valve IE predicted in-hospital death (p = 0.039, OR 2.258, 95% CI 1.043–4.888) and embolism (p = 0.017, OR 2.328, 95% CI 1.163–4.659), respectively. Conclusions: In this retrospective study, shock at admission independently predicted embolism during hospitalization in IE patients. Moreover, a new cardiac murmur at admission predicted the need for cardiac surgery. This emphasizes the importance of a comprehensive initial clinical evaluation in combination with imaging and microbiological data, in order to identify high-risk IE patients early.
URI (Уніфікований ідентифікатор ресурсу): http://e.ieu.edu.ua/handle/123456789/618
Розташовується у зібраннях:Європейська медична школа

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