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Название: Predictors of vessel quantitative flow ratio loss in patients with severely calcified lesions after rotational atherectomy.
Авторы: Zhou, Yu-he.;
Xu, Hai-mei.;
Zhao, Ying-ying.;
Zhu, Jing-dong.;
Xu, Hai-hua.;
Wang, Yan-qing.;
Hu, Ze-ping.;
Ключевые слова: percutaneous coronary intervention,
rotational atherectomy,
calcification,
quantitative flow ratio.
Дата публикации: 10-окт-2022
Издательство: Cardiology Journal .
Библиографическое описание: Cardiology Journal .-2023,vol.30,N3.
Краткий осмотр (реферат): Background: Previous studies have established that moderately to severely calcified lesions (MSCL) are associated with high rates of major adverse cardiovascular events, even when drug-eluting stents are implanted after rotational atherectomy (RA). Yet, the changes in coronary function indexes during follow-ups have never been investigated. The quantitative flow ratio (QFR), a novel coronary function index, has been increasingly adopted in daily practice in recent years. Methods: A total of 111 MSCL patients were retrospectively enrolled in this study. The vessel QFR (QFRv) loss was defined as post-percutaneous coronary intervention QFRv minus follow-up QFRv. The study subjects were divided into high QFRv loss (n = 51) and low QFRv loss (n = 60) groups according to the binary method. The obtained predictors of QFRv loss were then analyzed. Results: The results showed that the final burr-to-vessel ratio (B to V ratio) in the high QFRv loss group decreased significantly compared to the low QFRv loss group (p < 0.01). The univariate and multivariate regression analyses indicated that the final B to V ratio was an excellent predictor of QFRv loss. The cut-off value of the final B to V ratio for QFRv loss prediction was 0.50 (sensitivity: 50.98%, specificity: 68.33%, and area under the curve: 0.627 [95% confidence interval: 0.530–0.717], p < 0.05). Additionally, the target vessel failure incidence in the high QFRv loss group was higher than in the low QFRv loss group (p < 0.01). Conclusions: An increased burr-to-vessel ratio can prevent QFRv loss in patients with MSCLs after RA, an effect that might be closely associated with a low target vessel failure incidence. (Cardiol J 2023; 30, 3: 353–360)
URI (Унифицированный идентификатор ресурса): http://e.ieu.edu.ua/handle/123456789/615
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