The role of tranexamic acid in contemporary medicine.

Abstract

Tranexamic acid is a synthetic lysine derivative that operates by slowing the disintegration of blood clots. This restriction of plasmin activity increases the stability of blood clots, resulting in less bleeding and blood loss. Tranexamic acid also has an immediate effect on clot formation by increasing the activity of coagulation factors including factor IX and factor X. This increases clot stability and decreases bleeding.