Please use this identifier to cite or link to this item: http://e.ieu.edu.ua/handle/123456789/599
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dc.contributor.authorKoniari, Ioanna.;-
dc.contributor.authorArtopoulou, Eleni.;-
dc.contributor.authorMplani, Virginia.;-
dc.contributor.authorMulita, Francesk.;-
dc.contributor.authorAlexopoulou, Evangelia.;-
dc.contributor.authorChourdakis, Emmanouil.;-
dc.contributor.authorMohammed, Abo-Elseoud.;-
dc.contributor.authorGrigorios, Tsigkas.;-
dc.contributor.authorPanagiotopoulos, Ioannis.;-
dc.contributor.authorKounis, Nicholas.;-
dc.contributor.authorDimitrios, Velissaris.;-
dc.date.accessioned2023-06-01T06:30:06Z-
dc.date.available2023-06-01T06:30:06Z-
dc.date.issued2022-06-23-
dc.identifier.citationCardiology Journal .-2022.uk
dc.identifier.urihttp://e.ieu.edu.ua/handle/123456789/599-
dc.description.abstractHeart failure (HF) and atrial fibrillation (AF) are two cardiovascular (CV) entities that affect millions of individuals worldwide and their prevalence is translated into a significant impact on health care sys tems. The common pathophysiological pathways that these two share have created an important clinical interrelation, as the coexistence of HF and AF is associated with worse prognosis and treatment chal lenges. Renin–angiotensin–aldosterone system (RAAS), a critical mechanism in blood pressure (BP) control, was proved to be involved in the pathogenesis of both conditions contributing to their further coexistence. Successful control of BP is of great importance to the management of HF, crucial for the prevention of arrhythmiogenic substrates, while RAAS antagonists may possibly affect the development of new-onset AF as well. There are numerous studies that evaluated the effectiveness of RAAS blockade in AF/HF population and despite comparable or modest results, there is a well-established suggestion that RAAS blockers may contribute to a reduction of HF, CV events and recurrence of AF, along with their potential effective role in the new-onset AF prophylaxis. Angiotensin receptor blockers, according to the evidence, are more effective in that direction, followed by angiotensin converting enzyme inhibitors, whereas the data on aldosterone antagonists are not encouraging, yet do have the potential of significant CV disease modificators regardless of their effects on BP. (Cardiol J)uk
dc.language.isoenuk
dc.publisherCardiology Journal .uk
dc.subjectrenin–angiotensin–aldosterone system (RAAS) blockers,uk
dc.subjectatrial fibrillation,uk
dc.subjectheart failure,uk
dc.subjectangiotensin receptor blockers (ARBs),uk
dc.subjectangiotensin converting enzyme inhibitors (ACEIs),uk
dc.subjectaldosterone antagonists (AAs);uk
dc.titleAtrial fibrillation in heart failure patients: An update on renin–angiotensin–aldosterone system pathway blockade as a therapeutic and prevention target.uk
dc.typeArticleuk
Appears in Collections:Європейська медична школа

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