open access
The impact of first wave of the SARS-CoV-2 2019 pandemic in Poland on characteristics and outcomes of patients hospitalized due to stable coronary artery disease
open access
Abstract
Background: An investigation of baseline characteristics, treatment, and outcomes in patients with
stable coronary disease after the first wave of the severe acute respiratory syndrome coronavirus 2 (SARS-
-CoV-2) pandemic may provide valuable data and is beneficial for public health strategy in upcoming years.
Methods: A multi-institutional registry, including 10 cardiology departments, was searched for patients
admitted from June 2020 to October 2020. The baseline characteristics (age, gender, symptoms,
comorbidities), treatment (non-invasive, invasive, surgical), and hospitalization outcome (mortality,
myocardial infarction, stroke, composite endpoint — major adverse cardiac and cerebrovascular events
[MACCE]) were evaluated. The comparison was made to parameters presented by patients from the
same timeframe in 2019 (June–October). Multivariable analysis was performed.
Results: Number of hospitalized stable patients following lockdown was lower (2498 vs. 1903;
p < 0.0001). They were younger (68.0 vs. 69.0; p < 0.019), more likely to present with hypertension
(88.5% vs. 77.5%; p < 0.0001), diabetes (35.7% vs. 31.5%; p = 0.003), hyperlipidemia (67.9% vs.
55.4%; p < 0.0001), obesity (35.8% vs. 31.3%; p = 0.002), and more pronounced symptoms (Canadian
Cardiovascular Society [CCS] III and CCS class IV angina: 30.4% vs. 26.5%; p = 0.005). They
underwent percutaneous treatment more often (35.0% vs. 25.9%; p < 0.0001) and were less likely to be
referred for surgery (3.7% vs. 4.9%; p = 0.0001). There were no significant differences in hospitalization
outcome. New York Heart Association (NYHA) class IV for heart failure was a risk factor for both
mortality and MACCE in multivariate analysis.
Conclusions: The SARS-CoV-2 2019 pandemic affected the characteristics and hospitalization course
of stable angina patients hospitalized following the first wave. The hospitalization outcome was similar
in the analyzed time intervals. The higher prevalence of comorbidities raises concern regarding upcoming
years.
Abstract
Keywords
COVID-19, coronavirus, lockdown, coronary artery disease, pandemic
Title
The impact of first wave of the SARS-CoV-2 2019 pandemic in Poland on characteristics and outcomes of patients hospitalized due to stable coronary artery disease
Journal
Issue
Article type
Original Article
Pages
337-343
Published online
2022-10-04
Page views
889
Article views/downloads
329
DOI
10.5603/CJ.a2022.0094
Pubmed
Bibliographic record
Cardiol J 2023;30(3):337-343.
Keywords
COVID-19
coronavirus
lockdown
coronary artery disease
pandemic
Authors
Justyna Jankowska-Sanetra
Krzysztof Sanetra
Marta Konopko
Monika Kutowicz
Magdalena Synak
Krzysztof Milewski
Paweł Kaźmierczak
Łukasz Kołtowski
Piotr Paweł Buszman
- WHO COVID-19 situation report. . https://www.who.int/.
- Statistics related to COVID-19 infection, Primary Statistical Department. https://stat.gov.pl/.
- Hawranek M, Grygier M, Bujak K, et al. Characteristics of patients from the Polish Registry of Acute Coronary Syndromes during the COVID-19 pandemic: the first report. Kardiol Pol. 2021; 79(2): 192–195.
- Mafham M, Spata E, Goldacre R, et al. COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. Lancet. 2020; 396(10248): 381–389.
- Metzler B, Siostrzonek P, Binder RK, et al. Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage. Eur Heart J. 2020; 41(19): 1852–1853.
- De Filippo O, D'Ascenzo F, Angelini F, et al. Reduced Rate of Hospital Admissions for ACS during Covid-19 Outbreak in Northern Italy. N Engl J Med. 2020; 383(1): 88–89.
- Lazzerini M, Barbi E, Apicella A, et al. Delayed access or provision of care in Italy resulting from fear of COVID-19. Lancet Child Adolesc Health. 2020; 4(5): e10–e11.
- Marín-Jiménez I, Zabana Y, Rodríguez-Lago I, et al. COVID-19 and inflammatory bowel disease: questions arising from patient care and follow-up during the initial phase of the pandemic (February-April 2020). Gastroenterol Hepatol. 2020; 43(7): 408–413.
- Hammad TA, Parikh M, Tashtish N, et al. Impact of COVID-19 pandemic on ST-elevation myocardial infarction in a non-COVID-19 epicenter. Catheter Cardiovasc Interv. 2021; 97(2): 208–214.
- Pessoa-Amorim G, Camm CF, Gajendragadkar P, et al. Admission of patients with STEMI since the outbreak of the COVID-19 pandemic: a survey by the European Society of Cardiology. Eur Heart J Qual Care Clin Outcomes. 2020; 6(3): 210–216.
- Agrawal S, Makuch S, Dróżdż M, et al. The impact of the COVID-19 emergency on life activities and delivery of healthcare services in the elderly population. J Clin Med. 2021; 10(18).
- Guan WJ, Ni ZY, Hu Yu, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020; 382(18): 1708–1720.
- Zheng YY, Ma YT, Zhang JY, et al. COVID-19 and the cardiovascular system. Nat Rev Cardiol. 2020; 17(5): 259–260.
- Ganatra S, Hammond SP, Nohria A. The novel coronavirus disease (COVID-19) threat for patients with cardiovascular disease and cancer. JACC CardioOncol. 2020; 2(2): 350–355.
- Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229): 1054–1062.
- Holland D, Heald AH, Stedman M, et al. Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis. J Clin Pathol. 2021 [Epub ahead of print].
- Pettus J, Skolnik N. Importance of diabetes management during the COVID-19 pandemic. Postgrad Med. 2021; 133(8): 912–919.
- Banerjee M, Chakraborty S, Pal R. Diabetes self-management amid COVID-19 pandemic. Diabetes Metab Syndr. 2020; 14(4): 351–354.
- Clemmensen C, Petersen MB, Sørensen TIA. Will the COVID-19 pandemic worsen the obesity epidemic? Nat Rev Endocrinol. 2020; 16(9): 469–470.
- Lim MA, Huang I, Yonas E, et al. A wave of non-communicable diseases following the COVID-19 pandemic. Diabetes Metab Syndr. 2020; 14(5): 979–980.
- Gopalan HS, Misra A. COVID-19 pandemic and challenges for socio-economic issues, healthcare and National Health Programs in India. Diabetes Metab Syndr. 2020; 14(5): 757–759.
- Piepoli M, Hoes A, Agewall S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur J Prev Cardiol. 2016; 23(11): NP1–NP96.
- Winzer EB, Woitek F, Linke A. Physical activity in the prevention and treatment of coronary artery disease. J Am Heart Assoc. 2018; 7(4): e007725.
- Kwok CS, Gale CP, Curzen N, et al. Impact of the COVID-19 pandemic on percutaneous coronary intervention in England: insights from the British Cardiovascular Intervention Society PCI Database Cohort. Circ Cardiovasc Interv. 2020; 13(11): e009654.
- Ishii H, Amano T, Yamaji K, et al. Implementation of Percutaneous Coronary Intervention During the COVID-19 Pandemic in Japan: Nationwide Survey Report of the Japanese Association of Cardiovascular Intervention and Therapeutics for Cardiovascular Disease. Circ J. 2020; 84(12): 2185–2189.
- Moreno R, Díez JL, Diarte JA, et al. Consequences of canceling elective invasive cardiac procedures during COVID-19 outbreak. Catheter Cardiovasc Interv. 2021; 97(5): 927–937.
- Maron D, Hochman J, Reynolds H, et al. Initial invasive or conservative strategy for stable coronary disease. N Engl J Med. 2020; 382(15): 1395–1407.
- Neumann FJ, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. EuroIntervention. 2019; 14(14): 1435–1534.
- Gaudino M, Chikwe J, Hameed I, et al. Response of Cardiac Surgery Units to COVID-19: An Internationally-Based Quantitative Survey. Circulation. 2020; 142(3): 300–302.